Ryan Cawood

Oxford Genetics secures £3 million Series A Follow On investment led by Mercia

OXGENE™, a leading life sciences solutions provider, is pleased to report that it has more than doubled its annual revenue in the financial year just closed, in the third consecutive year of 100% year on year revenue growth. OXGENE uses its expertise in mammalian cell engineering across gene therapy, gene editing and antibody therapeutics to develop novel technology platforms that facilitate the discovery, development and manufacture of new biologics.

OXGENE’s success this year has been fuelled by a combination of strategic licensing agreements and service delivery projects. This year, OXGENE has set the scene for industry-wide adoption of their leading AAV and lentiviral transient gene therapy production technologies by licensing to both CMOs and therapeutics manufacturers across the globe. Most recently, they partnered with Fujifilm Diosynth Biotechnologies (FDB), who will use OXGENE’s proprietary AAV production platform, comprising optimised Helper, Rep/Cap and Gene of Interest plasmids, used in combination with a clonal suspension HEK293 cell line, for customers engaged in process development and GMP manufacture of gene therapies at FDB’s College Station, Texas site.

OXGENE have also signed multiple other licensing agreements with companies in the US, Asia and Europe, demonstrating the company’s increasing global reach.

OXGENE have cemented their reputation as market leaders for high throughput CRISPR based engineering through the extension of their partnership with Abcam plc, as well as for the generation of complex disease models with projects for customers including Artios Pharma, who specialise in the development of breakthrough cancer treatments targeting DNA Damage Response pathways.

Maintaining a significant level of investment in R&D has ensured that OXGENE remains future focussed, building a pipeline of innovative new technologies that it aims to bring to market in the first half of the new
financial year. This includes its novel mammalian display antibody discovery system, which enables the discovery of antibodies against previously intractable membrane proteins, and transformative solutions for scalable, stable gene therapy manufacture.

The final quarter of OXGENE’s financial year has been marked by their quick response to join the fight against COVID-19. The company has initiated a number of projects to contribute to COVID19 diagnostic, vaccine and therapeutic programmes, including entering a collaboration with The Native Antigen Company to scale up manufacture of COVID19 antigens. The company enters the new financial year fresh from the completion of a successful fundraising round from existing investors, which will be used to expand their current facilities, to support further growth.


Jo Bath, OXGENE’s Chief Operating Officer says, “OXGENE has once again more than doubled its revenue, with less than a 50% increase in headcount. This is testament not only to the hard work and effective management of our team here, but also to the strength of our automation platform, and our focussed, but flexible, approach to business and technology development.”
She continues, “This has been a year of continued growth and transition as we have established ourselves as a leading life sciences solutions provider. We’re extremely proud of everything we’ve accomplished this year, and look forward to introducing more innovative, game changing technologies to market in the year ahead.”

About OXGENE

OXGENE™ combines precision engineering and breakthrough science with advanced robotics and bioinformatics to accelerate the rational design, discovery and manufacture of cell and gene therapies across three core areas: gene therapy, gene editing and antibody therapeutics.

Gene therapy: We’re transforming the vision of truly scalable gene therapies into a reality; progressing our industry leading transient gene therapy systems towards alternative technologies for scalable, stable
manufacturing solutions.

Gene editing: We have automated gene editing to deliver CRISPR engineered cell lines at unparalleled speed, scale and quality and generate complex disease models in mammalian cells.

Antibody therapeutics: We’re employing a novel proprietary mammalian display technology to discover antibodies against previously intractable membrane proteins.

OXGENE™ works at the edge of impossible in mammalian cell engineering. Our scientific expertise and technology solutions address industry bottlenecks. For more information, please visit www.oxgene.com

Contact

Sophie Lutter, Scientific Communications and Marketing Manager
Tel: (+44) 7841651970
Email: [email protected]

Manoj Ranaweera

Manoj has founded, failed and successfully exited from a number of technology product companies as well as support organisations since 2004. Among them, Northern Tech Awards and edocr.com were acquired by GP Bullhound and Accusoft, Inc respectively. Today, Manoj is building a trusted support network for technology companies. He is working with founding teams to help them accelerate including raising investment and M&A.